| Bioactivity | LU-005i is a potent inhibitor of β5i subunit of immunoproteasomes (IC50 = 6.6 nM), selective over β5c subunit (IC50 = 287 nM)[1]. |
| Target | β5i subunit of immunoproteasomes (IC50 = 6.6 nM), β5c subunit of immunoproteasomes (IC50 = 287 nM) |
| Name | LU-005i |
| CAS | 1620107-33-6 |
| Formula | C31H46N4O7 |
| Molar Mass | 586.72 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Rezvan Moallemian, et al. Immunoproteasome inhibitor DPLG3 attenuates experimental colitis by restraining NF-κB activation.Biochem Pharmacol. 2020 Jul:177:113964. |