Bioactivity | LSP-GR3 is a novel chemically-modified RNA oligonucleotides, called splice modulating oligomers (SMOs), which potently and specifically modulate GluR alternative splicing to GluR3-flip expression throughout the CNS. |
Name | LSP-GR3 |
CAS | 1235945-37-5 |
Sequence | RNA, (2'-O-Methyl Phosphorothioate 5'-GCUAGGUUUACGGGACCUCU-3') |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Modulation of pre-mRNA using splice modulating oligonucleotides as therapeutic agents in the treatment of disease. WO2010083338A2 |