Bioactivity | LSP-249 (example 35), extracted from patent WO2016011209A1, is a plasma kallikrein inhibitor under the study for angioedema, with an EC50 less than 100 nM in cell[1]. | ||||||||||||
Target | EC50:< 100 nM (kallikrein in cell). | ||||||||||||
Name | LSP-249 | ||||||||||||
CAS | 1801253-04-2 | ||||||||||||
Formula | C24H22ClN5O | ||||||||||||
Molar Mass | 431.92 | ||||||||||||
Appearance | Solid | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
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Reference | [1]. Andrew Mcdonald, et al. Therapeutic inhibitory compounds. Patent. WO2016011209A1. |