Bioactivity | LSD1-UM-109 is a ighly potent and reversible LSD1 inhibitor with an IC50 of 3.1 nM. LSD1-UM-109 inhibits cell growth with IC50 values of 0.6 nM in the MV4;11 acute leukemia cell line and 1.1 nM in the H1417 small-cell lung cancer cell line[1]. |
Name | LSD1-UM-109 |
CAS | 2252446-26-5 |
Formula | C29H27FN6 |
Molar Mass | 478.56 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Canhui Zheng, et al. Discovery of Pyrrolo[2,3- c]pyridines as Potent and Reversible LSD1 Inhibitors. ACS Med Chem Lett. 2023 Sep 21;14(10):1389-1395. |