| Bioactivity | LRRK2 inhibitor 1 is a potent, selective and oral LRRK2 inhibitor with an pIC50 of 6.8. | ||||||||||||
| Target | pIC50: 6.8 nM (LRRK2) | ||||||||||||
| Name | LRRK2 inhibitor 1 | ||||||||||||
| CAS | 1802525-61-6 | ||||||||||||
| Formula | C20H23N5O4 | ||||||||||||
| Molar Mass | 397.43 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Ding X, et al. Discovery of 4-ethoxy-7H-pyrrolo[2,3-d]pyrimidin-2-amines as potent, selective and orally bioavailable LRRK2 inhibitors. Bioorg Med Chem Lett. 2018 May 15;28(9):1615-1620. |