PeptideDB

LQVTDSGLYRCVIYHPP TFA

CAS: F: C91H138F3N23O27S W: 2075.27

LQVTDSGLYRCVIYHPP (LP17) TFA is a triggering receptor expressed on myeloid cells (TREM-1) inhibitory peptide. LQVTDSGLYR
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Bioactivity LQVTDSGLYRCVIYHPP (LP17) TFA is a triggering receptor expressed on myeloid cells (TREM-1) inhibitory peptide. LQVTDSGLYRCVIYHPP TFA substantially alleviates ischemia-induced infarction and neuronal injury. LQVTDSGLYRCVIYHPP TFA can get access into brain and block TREM-1[1].
Invitro LQVTDSGLYRCVIYHPP (LP17) (1 or 10 μM; 24 h) substantially decreases mRNA levels of pro-inflammatory cytokines and chemokines after reoxygenation and remarkably attenuates extracellular protein levels of IL-1β and IL-18 in a microglia oxygen-glucose deprivation (OGD) model[1].LQVTDSGLYRCVIYHPP (LP17) (10 μM; 24 h) interacts with microglial SYK[1]. RT-PCR[1] Cell Line:
Name LQVTDSGLYRCVIYHPP TFA
Shortening LQVTDSGLYRCVIYHPP
Formula C91H138F3N23O27S
Molar Mass 2075.27
Transport Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture and light

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)