PeptideDB

LP10

CAS: 1025400-45-6 F: C24H28N4O2 W: 404.50

LP10 is a non-azole CYP51 inhibitor with activity against Trypanosoma cruzi infection. Treatment with LP10 blocks the 14
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Bioactivity LP10 is a non-azole CYP51 inhibitor with activity against Trypanosoma cruzi infection. Treatment with LP10 blocks the 14α-demethylation step, leading to disruption of the parasite cell membrane and ultimately triggering the death of important clinically relevant amoeba stages[1].
CAS 1025400-45-6
Formula C24H28N4O2
Molar Mass 404.50
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. A nonazole CYP51 inhibitor cures Chagas' disease in a mouse model of acute infection