Bioactivity | LP10 is a non-azole CYP51 inhibitor with activity against Trypanosoma cruzi infection. Treatment with LP10 blocks the 14α-demethylation step, leading to disruption of the parasite cell membrane and ultimately triggering the death of important clinically relevant amoeba stages[1]. |
CAS | 1025400-45-6 |
Formula | C24H28N4O2 |
Molar Mass | 404.50 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. A nonazole CYP51 inhibitor cures Chagas' disease in a mouse model of acute infection |