| Bioactivity | LM985 is one of a series of compounds based on the flavone ring structure, with anti-tumor activities. |
| Invitro | LM985 shows inhibitory effects against MAC 13 cells, but MAC 15A cells are less sensitive to LM985[1]. |
| In Vivo | LM985 (200 mg/kg, s.c.) shows moderate activity against MAC 13, and after repeated injection 7 days, responses are considerably enhanced[2]. |
| Name | LM985 |
| CAS | 87626-56-0 |
| Formula | C23H25NO4 |
| Molar Mass | 379.45 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. M. C. Bibby, et al. Factors involved in the anti-cancer activity of the investigational agents LM985 (flavone acetic acid ester) and LM975 (flavone acetic acid). Br J Cancer. 1987 Feb; 55(2): 159-163. [2]. J. A. Double, et al. Pharmacokinetics and anti-tumour activity of LM985 in mice bearing transplantable adenocarcinomas of the colon. Br J Cancer. 1986 Oct; 54(4): 595-600. |