| Bioactivity | LIN28 inhibitor LI71 enantiomer is the enantiomer of LIN28 inhibitor LI71 with less active. LIN28 inhibitor LI71 is a potent and cell-permeable LIN28 inhibitor, which abolishes LIN28-mediated oligouridylation with an IC50 of 7 uM[1]. | ||||||||||||
| Target | LIN280 | ||||||||||||
| Name | LIN28 inhibitor LI71 enantiomer | ||||||||||||
| CAS | 956189-58-5 | ||||||||||||
| Formula | C21H21NO3 | ||||||||||||
| Molar Mass | 335.40 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Wang L, et al. Small-Molecule Inhibitors Disrupt let-7 Oligouridylation and Release the Selective Blockade of let-7 Processing by LIN28. Cell Rep. 2018;23(10):3091-3101. |