LIMK-IN-1_product_DataBase

CAS: 1116571-01-7 F: C20H21BrN8 W: 453.34

LIMK-IN-1 (Compound 14) is an inhibitor ofLIM-Kinase (LIMK), with IC50s of 0.5 nM and 0.9 nM for LIMK1 and LIMK2, respec

This product is for research use only, not for human use. We do not sell to patients.

Bioactivity	LIMK-IN-1 (Compound 14) is an inhibitor of LIM-Kinase (LIMK), with IC50s of 0.5 nM and 0.9 nM for LIMK1 and LIMK2, respectively. LIMK-IN-1 can be used for ocular hypertension and associated glaucoma research[1].
Invitro	LIMK-IN-1 (Compound 14) (100 nM) 在猪眼灌注测定中使流出系数增加约 30%[1]。
Name	LIMK-IN-1
CAS	1116571-01-7
Formula	C20H21BrN8
Molar Mass	453.34
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Harrison BA, et.al. Novel class of LIM-kinase 2 inhibitors for the treatment of ocular hypertension and associated glaucoma. J Med Chem. 2009 Nov 12;52(21):6515-8.

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