| Bioactivity | LIH383 is an agonist of ACKR3 (CXCR7) (EC50=0.61 nM). LIH383 efficiently induces the recruitment of β-arrestin to ACKR3 but does not trigger typical G protein signaling[1]. |
| CAS | 2866266-58-0 |
| Sequence | Phe-Gly-Gly-Phe-Met-Arg-Arg-Lys-NH2 |
| Shortening | FGGFMRRK-NH2 |
| Formula | C45H72N16O8S |
| Molar Mass | 997.22 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Meyrath M, et al. The atypical chemokine receptor ACKR3/CXCR7 is a broad-spectrum scavenger for opioid peptides. Nat Commun. 2020 Jun 19;11(1):3033. |