| Bioactivity | LE01 is a drug-linker conjugate for ADC. LE01 contains a ADC linker and a DNA topoisomerase I inhibitor DXd (HY-13631D). LE01 can be used to synthesize HER2-targeting ADC (HER2-LE01)[1]. |
| CAS | 2718125-83-6 |
| Formula | C55H61FN10O14 |
| Molar Mass | 1105.13 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Yifan Zhang, et al. Evaluation of Double Self-Immolative Linker-Based Antibody-Drug Conjugate FDA022-BB05 with Enhanced Therapeutic Potential. J Med Chem. 2024 Nov 14;67(21):19852-19873. |
LE01
CAS: 2718125-83-6 F: C55H61FN10O14 W: 1105.13
LE01 is a drug-linker conjugate for ADC. LE01 contains a ADC linker and a DNA topoisomerase I inhibitor DXd (HY-13631D).
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