Bioactivity | LDN-193665 is a Tau kinase inhibitor with tauopathy-modifying activity. LDN-193665 inhibits Tau phosphorylation, improves tauopathy in animal models, reduces Sarkosyl-insoluble Tau, and restores memory. It may be necessary to simultaneously target multiple kinases to effectively inhibit tauopathies. |
CAS | 1289638-16-9 |
Formula | C15H11FN4OS |
Molar Mass | 314.34 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Diaminothiazoles modify Tau phosphorylation and improve the tauopathy in mouse models |