LCB 03-0110_product_DataBase

Bioactivity	LCB 03-0110, a thienopyridine derivative, is a potent pan-discoidin domain receptor/c-Src family tyrosine kinase inhibitor. LCB 03-0110 suppresses scar formation by inhibiting fibroblast and macrophage activation[1].
Invitro	LCB 03-0110 抑制转化生长因子 β1 和 I 型胶原诱导的原代真皮成纤维细胞的增殖和迁移[1]。
In Vivo	LCB 03-0110 可抑制愈合伤口中肌成纤维细胞和巨噬细胞的积累，并减少兔耳伤口闭合后肥厚性疤痕的形成[1]。
Name	LCB 03-0110
CAS	1228102-01-9
Formula	C24H23N3O2S
Molar Mass	417.52
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Sun X, et, al. LCB 03-0110, a novel pan-discoidin domain receptor/c-Src family tyrosine kinase inhibitor, suppresses scar formation by inhibiting fibroblast and macrophage activation. J Pharmacol Exp Ther. 2012 Mar;340(3):510-9.

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