| Bioactivity | LC kinetic stabilizer-1 (compound 21) is a potent and selective amyloidogenic immunoglobulin light chain kinetic stabilizer with EC50s of 140 and 74.1 nM for WIL-FL* and WIL-FL* T46L/F49Y, respectively. WIL-FL is an amyloidogenic FL LC dimer[1]. |
| Name | LC kinetic stabilizer-1 |
| CAS | 2495750-19-9 |
| Formula | C27H31N5O3 |
| Molar Mass | 473.57 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Yan NL, et al. Amyloidogenic immunoglobulin light chain kinetic stabilizers comprising a simple urea linker module reveal a novel binding sub-site. Bioorg Med Chem Lett. 2022;60:128571. |
LC kinetic stabilizer-1
CAS: 2495750-19-9 F: C27H31N5O3 W: 473.57
LC kinetic stabilizer-1 (compound 21) is a potent and selective amyloidogenic immunoglobulin light chain kinetic stabili
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