| Bioactivity | LAH5 is an amphipathic cell-penetrating peptide. LAH5 effectively delivers CRISPR-Cas9 components into the nuclei of target cells by forming nanocomplexes with both RNP and RNP/HDR cargo[1]. |
| Name | LAH5 |
| CAS | 476169-12-7 |
| Sequence | Lys-Lys-Ala-Leu-Leu-Ala-Leu-Ala-Leu-His-His-Leu-Ala-His-Leu-Ala-His-His-Leu-Ala-Leu-Ala-Leu-Lys-Lys-Ala |
| Shortening | KKALLALALHHLAHLAHHLALALKKA |
| Formula | C132H224N40O27 |
| Molar Mass | 2803.44 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Kichler A, et al. Histidine-rich amphipathic peptide antibiotics promote efficient delivery of DNA into mammalian cells. Proc Natl Acad Sci U S A. 2003 Feb 18;100(4):1564-8. [2]. Öktem M, et al. Amphipathic Cell-Penetrating Peptide-Aided Delivery of Cas9 RNP for In Vitro Gene Editing and Correction. Pharmaceutics. 2023 Oct 20;15(10):2500. |
LAH5
CAS: 476169-12-7 F: C132H224N40O27 W: 2803.44
LAH5 is an amphipathic cell-penetrating peptide. LAH5 effectively delivers CRISPR-Cas9 components into the nuclei of tar
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