| Bioactivity | LAH-1 is a c-Met inhibitor with oral activity and membrane permeability with an IC50 of 49 nM. LAH-1 has anticancer activity and can induce apoptosis, migration, and invasion[1]. |
| Target | IC50: 49 nM (c-Met). |
| Name | LAH-1 |
| CAS | 3018150-68-7 |
| Formula | C27H22F2N6O5 |
| Molar Mass | 548.50 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Sima L,et al. Discovery of LAH-1 as potent c-Met inhibitor for the treatment of non-small cell lung cancer[J]. Journal of Enzyme Inhibition and Medicinal Chemistry, 2024, 39(1): 2286435. |