| Bioactivity | L57 exhibits high affinity to the low-density lipoprotein receptor-related protein 1 (LRP1) with Ki of 45 nM. L57 exhibits blood-brain barrier (BBB) permeability and plasma stability. L57 can be utilized as the carrier for CNS drug delivery[1]. |
| CAS | 2378836-93-0 |
| Sequence | Thr-Trp-Pro-Lys-His-Phe-Asp-Lys-His-Thr-Phe-Tyr-Ser-Ile-Leu-Lys-Leu-Gly-Lys-His |
| Shortening | TWPKHFDKHTFYSILKLGKH |
| Formula | C120H175N31O27 |
| Molar Mass | 2483.87 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Sakamoto K, et al., A novel LRP1-binding peptide L57 that crosses the blood brain barrier. Biochem Biophys Rep. 2017 Aug 12;12:135-139. |
L57
CAS: 2378836-93-0 F: C120H175N31O27 W: 2483.87
L57 exhibits high affinity to the low-density lipoprotein receptor-related protein 1 (LRP1) with Ki of 45 nM. L57 exhibi
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