| Bioactivity | L-Palmitoylcarnitine chloride, a long-chain acylcarnitine and a fatty acid metabolite, accumulates in the sarcolemma and deranges the membrane lipid environment during ischaemia. L-Palmitoylcarnitine chloride inhibits KATP channel activity, without affecting the single channel conductance, through interaction with Kir6.2[1]. |
| Invitro | L-Palmitoylcarnitine (1 µM) inhibits KATP channel activity, without affecting the single channel conductance, through interaction with Kir6.2. L-Palmitoylcarnitine simultaneously enhances the ATP sensitivity of the channel (IC50 fell from 62 to 30 µM)[1].Modulation of the membrane lipid environment caused by L-Palmitoylcarnitine alters the KATP channel function mainly through the interaction with endogenous PI cascade, especially PIP2[1]. |
| Name | L-Palmitoylcarnitine chloride |
| CAS | 18877-64-0 |
| Formula | C23H46ClNO4 |
| Molar Mass | 436.07 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
L-Palmitoylcarnitine chloride
CAS: 18877-64-0 F: C23H46ClNO4 W: 436.07
L-Palmitoylcarnitine chloride, a long-chain acylcarnitine and a fatty acid metabolite, accumulates in the sarcolemma and
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