Bioactivity | L-Ornithine ((S)-2,5-Diaminopentanoic acid) is a non-proteinogenic amino acid, is mainly used in urea cycle removing excess nitrogen in vivo. L-Ornithine shows nephroprotective[1][2]. |
Invitro | L-Ornithine (0-10 mM) activates the CaSR in a concentration-dependent manner and exerts effects on Ca2+ signaling in HK-2 cells[2].L-Ornithine (10 mM) activates TRPC channels mediated Ca2+ entry pathway in HK-2 cells[2].L-Ornithine (100 or 300 μM; 24 h) shows the protection against ROS generation in HK-2 cells via ROCE pathway[2].L-Ornithine (10 μM) can protect the ROS and oxidative damage in HK-2 cells exposed to H2O2[2]. |
Name | L-Ornithine |
CAS | 70-26-8 |
Formula | C5H12N2O2 |
Molar Mass | 132.16 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | 4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |