Bioactivity | L-Isoleucine-13C6,15N is 13C and 15N labeled L-isoleucine. L-isoleucine is a nonpolar hydrophobic amino acid[1]. L-Isoleucine is an essential amino acid. |
Invitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[2]. |
Name | L-Isoleucine-13C6,15N |
CAS | 202468-35-7 |
Formula | 13C6H1315NO2 |
Molar Mass | 138.12 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Arkhipov SG, et al. New hydrophobic L-amino acid salts: maleates of L-leucine, L-isoleucine and L-norvaline. Acta Crystallogr C Struct Chem. 2015 Jul;71(Pt 7):584-92. [2]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. |