| Bioactivity | L-Hyoscyamine sulfate (Daturine sulfate), a natural plant tropane alkaloid, is a potent and competitive muscarinic receptor (MR) antagonist. L-Hyoscyamine sulfate is a levo-isomer to Atropine (HY-B1205)[1][2]. |
| In Vivo | L-Hyoscyamine sulfate (Daturine sulfate; 5-20 mg/kg; iv) prolongs the migrating MMC cycle length[1]. Animal Model: |
| Name | L-Hyoscyamine sulfate |
| CAS | 620-61-1 |
| Formula | C17H24NO5S0.5 |
| Molar Mass | 338.41 |
| Appearance | Solid |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |
| Reference | [1]. Lars Göran Axelsson, et al. Regulatory role of 5-HT and muscarinic receptor antagonists on the migrating myoelectric complex in rats. Eur J Pharmacol. 2003 Apr 25;467(1-3):211-8. [2]. Harald John, et al. Application of an enantioselective LC-ESI MS/MS procedure to determine R- and S-hyoscyamine following intravenous atropine administration in swine. Drug Test Anal. Mar-Apr 2012;4(3-4):194-8. |
L-Hyoscyamine sulfate
CAS: 620-61-1 F: C17H24NO5S0.5 W: 338.41
L-Hyoscyamine sulfate (Daturine sulfate), a natural plant tropane alkaloid, is a potent and competitive muscarinic recep
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