| Bioactivity | L-Fd4A is an adenine derivative. L-Fd4A has anti-human immunodeficiency virus (HIV) (EC50=1.5 μM) and anti-hepatitis B virus (HBV) (EC50=1.7 μM) activity. L-Fd4A has low cytotoxicity[1]. |
| Invitro | L-Fd4A (compound 36) has no toxicity in PBM, Vero and CEM cells. L-Fd4A shows any effect on mitochondrial DNA of CEM cells upon long-term exposure[1]. |
| Name | L-Fd4A |
| CAS | 210474-65-0 |
| Formula | C10H10FN5O2 |
| Molar Mass | 251.22 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Lee K, et, al. Synthesis and anti-HIV and anti-HBV activities of 2'-fluoro-2', 3'-unsaturated L-nucleosides. J Med Chem. 1999 Apr 8;42(7):1320-8. |