Bioactivity | L-Aspartic acid-13C is a 13C labeled L-Aspartic acid. L-Aspartic acid is is an amino acid, shown to be a suitable prodrug for colon-specific drug deliverly[1][2]. | ||||||||||||
Invitro | L-Aspartic acid is shown to be a suitable prodrug for colon-specific drug deliverly[1]. L-[3H]Asp remaining in the brain at 5 min is increased by 206 and 178% by preadministration of 100 mM L-Aspartic acid and 100 mM L-Glu, respectively, whereas 100 mM D-Asp does not affect L-[3H]Asp efflux transport. That value for L-[3H]Glu at 20 min is increased by 145 and 156% by coadministration with 100 mM L-Aspartic acid and 100 mM L-Glu, respectively, but not by D-Asp. It is interesting that the apparent efflux rate of L-Aspartic acid across the BBB is sevenfold faster than that of L-Glu[2]. | ||||||||||||
Name | L-Aspartic acid-13C | ||||||||||||
CAS | 81201-97-0 | ||||||||||||
Formula | C313CH7NO4 | ||||||||||||
Molar Mass | 134.10 | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
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