| Bioactivity | L-764406 is a non-thiazolidinedione (TZD)-type PPARg nuclear receptor ligand with high affinity. L-764406 has significant binding ability to PPARg (IC50=70 nM). L-764406 exhibited partial agonist activity and induced expression of the adipocyte-specific gene aP2 in chimeric receptors expressing the PPARg LBD and the corresponding reporter gene, as well as in 3T3-L1 cells. In contrast, L-764406 showed no activity in cells transfected with chimeric receptors containing PPARa or PPARd LBDs[1]. |
| Target | PPARg Nuclear Receptor |
| CAS | 227002-04-2 |
| Formula | C15H11ClN2O2S |
| Molar Mass | 318.78 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. L-764406 Is a Partial Agonist of Human Peroxisome Proliferator-activated Receptor g |
L-764406
CAS: 227002-04-2 F: C15H11ClN2O2S W: 318.78
L-764406 is a non-thiazolidinedione (TZD)-type PPARg nuclear receptor ligand with high affinity. L-764406 has significan
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