| Bioactivity | L-760735 is a high affinity, selective and orally active NK1 receptor antagonist with an IC50 of 0.19 nM for human NK1 receptors. L-760735 exhibits anxiolytic and antidepressant-like effects[1]. |
| Name | L-760735 |
| CAS | 188923-01-5 |
| Formula | C26H29ClF7N5O2 |
| Molar Mass | 611.98 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Harrison T, et al. An orally active, water-soluble neurokinin-1 receptor antagonist suitable for both intravenous and oral clinical administration. J Med Chem. 2001 Nov 22;44(24):4296-9. |
L-760735
CAS: 188923-01-5 F: C26H29ClF7N5O2 W: 611.98
L-760735 is a high affinity, selective and orally active NK1 receptor antagonist with an IC50 of 0.19 nM for human NK1 r
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