| Bioactivity | L-751788 is a selective inhibitor of type I of 5α-reductase. L-751788 does not have a significant impact on the differentiation of the external genitalia in animals. When administered orally to pregnant rhesus monkeys, L-751788 (2, 10 mg/kg) did not cause abnormalities in fetal external genitalia[1]. |
| CAS | 166174-54-5 |
| Formula | C26H36ClNO2 |
| Molar Mass | 430.02 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Voegeli R, et al. 5a-Reductase and Its Inhibitors[M]//Acne and Its Therapy. CRC Press, 2007: 181-216. [2]. Prahalada S, et al. Effects of finasteride, a type 2 5‐alpha reductase inhibitor, on fetal development in the rhesus monkey (Macaca mulatta)[J]. Teratology, 1997, 55(2): 119-131. |