PeptideDB

L-741671

CAS: 187724-85-2 F: C23H22F6N4O2 W: 500.44

L-741671 is a selective and brain-permeable antagonist of neurokininl (hNKI) receptor, with Kis of 64 nM, 0.03 nM and 0.
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This product is for research use only, not for human use. We do not sell to patients.

Bioactivity L-741671 is a selective and brain-permeable antagonist of neurokininl (hNKI) receptor, with Kis of 64 nM, 0.03 nM and 0.7 nM in rat, human and ferret, respectively[1].
CAS 187724-85-2
Formula C23H22F6N4O2
Molar Mass 500.44
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. F D Tattersall, et al. Tachykinin NK1 receptor antagonists act centrally to inhibit emesis induced by the chemotherapeutic agent cisplatin in ferrets. Neuropharmacology. 1996;35(8):1121-9.