| Bioactivity | L-739750 is a selective protein farnesyltransferase (PFTase) inhibitor (IC50: 0.4 nM). PFTase utilizes farnesyl diphosphate to farnesylate the cysteine residue of protein substrates having a C-terminal CAAX motif. L-739750 is a selective CAAX peptidomimetic[1][2]. |
| CAS | 160141-08-2 |
| Formula | C23H39N3O6S2 |
| Molar Mass | 517.70 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. 1. Kohl NE, et al. Protein farnesyltransferase inhibitors block the growth of ras-dependent tumors in nude mice. Proc Natl Acad Sci U S A. 1994 Sep 13;91(19):9141-5. [2]. Koblan KS, et al. NMR studies of novel inhibitors bound to farnesyl-protein transferase. Protein Sci. 1995 Apr;4(4):681-8. |
L-739750
CAS: 160141-08-2 F: C23H39N3O6S2 W: 517.70
L-739750 is a selective protein farnesyltransferase (PFTase) inhibitor (IC50: 0.4 nM). PFTase utilizes farnesyl diphosph
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.