| Bioactivity | L-739749 is a farnesyl transferase inhibitor. L-739749 inhibits the selective hypersensitivity of JMML cells to granulocyte-macrophage colony-stimulating factor (GM-CSF) by blocking the prenylation of Ras. L-739749 exhibits a strong inhibitory effect on the growth of primary human JMML cells in vitro[1]. |
| CAS | 156511-34-1 |
| Formula | C24H41N3O6S2 |
| Molar Mass | 531.73 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Emanuel P D, et al. Inhibition of juvenile myelomonocytic leukemia cell growth in vitro by farnesyltransferase inhibitors: Presented in part at the Thirty-Ninth American Society of Hematology Meeting, San Diego, CA, December 5-9, 1997[J]. Blood, The Journal of the American Society of Hematology, 2000, 95(2): 639-645. |
L-739749
CAS: 156511-34-1 F: C24H41N3O6S2 W: 531.73
L-739749 is a farnesyl transferase inhibitor. L-739749 inhibits the selective hypersensitivity of JMML cells to granuloc
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.