| Bioactivity | L-656224 is an orally active, potent and selective inhibitor of leukotriene biosynthesis in intact rat and human leukocytes and CXBG mastocytoma cells (IC50 values, 18-240 nM) and of human leukocyte and porcine leukocyte 5-lipoxygenase (IC50, 4 x 10-7 M). L-656224 is promising for research of asthma and peripheral analgesic agents[1]. |
| CAS | 102612-16-8 |
| Formula | C20H21ClO3 |
| Molar Mass | 344.83 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Belanger P, et al. L-656,224 (7-chloro-2-[(4-methoxyphenyl)methyl]-3- methyl-5-propyl-4-benzofuranol): a novel, selective, orally active 5-lipoxygenase inhibitor. Can J Physiol Pharmacol. 1987 Dec;65(12):2441-8. |