| Bioactivity | L 655240 is thromboxane antagonist. L 655240 attenuates early ischemia- and reperfusion-induced arrhythmias in a canine model of coronary artery occlusion. L 655240 also involves in cancer and autoimmune disorders[1]. |
| Invitro | L 655240 (7 nM) 抑制人血小板中内过氧化物诱导的聚集[1]。 |
| In Vivo | L 655240 (0.3 mg/kg；静脉注射；单次剂量) 改变犬类模型的发热率、动脉和肺动脉血压以及心输出量[1]。 |
| Name | L 655240 |
| CAS | 103253-15-2 |
| Formula | C21H21ClFNO2 |
| Molar Mass | 373.85 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Wainwright CL, et al. The effects of L655,240, a selective thromboxane and prostaglandin endoperoxide antagonist, on ischemia- and reperfusion-induced cardiac arrhythmias. J Cardiovasc Pharmacol. 1988 Sep;12(3):264-71. |
L 655240
CAS: 103253-15-2 F: C21H21ClFNO2 W: 373.85
L 655240 is thromboxane antagonist. L 655240 attenuates early ischemia- and reperfusion-induced arrhythmias in a canine
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