Bioactivity | L-646462 is an antagonist of dopamine and 5-HT, with selectivity for the peripheral system (the central/peripheral activity ratio of L-646462 is 143). L-646462 can be used in research related to nausea, vomiting, and associated neurological disorders[1]. |
CAS | 89149-85-9 |
Formula | C27H27N3O4 |
Molar Mass | 457.52 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Williams M, et al. L-646,462, a cyproheptadine-related antagonist of dopamine and serotonin with selectivity for peripheral systems[J]. Journal of Pharmacology and Experimental Therapeutics, 1984, 229(3): 775-781. |