| Bioactivity | L-364918 is a potent and selective oxytocin and arginine vasopressin antagonist with Ki values of 30, 1300, 2400 nM for OT, AVP-V1, AVP-V2, respectively. L-364918 has the potential for the research of preterm labor and disturbances in water balance[1]. |
| Invitro | L-364918 (0-1 mM) 剂量依赖性地抑制 AVP (HY-P0049) 刺激的肌醇磷酸盐在预先用肌醇标记的肝细胞中的积累，其 IC50 值为 8.6 µM[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> L-364918 相关抗体: |
| CAS | 122211-31-8 |
| Formula | C40H54N8O6 |
| Molar Mass | 742.91 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Pettibone DJ, et al. A structurally unique, potent, and selective oxytocin antagonist derived from Streptomyces silvensis. Endocrinology. 1989 Jul;125(1):217-22. |