| Bioactivity | L-2'-Fd4C, is an l-nucleoside analogue. L-2'-Fd4C has anti-human immunodeficiency virus (HIV) and anti-hepatitis B virus (HBV) activity[1]. |
| Invitro | L-2'-Fd4C (0-10 μM; 9 d; HepG2-2.2.15 cells) inhibits anti-hepatitis B virus (HBV) replication with an EC50 value of 0.002 μM[1]. |
| In Vivo | L-2'-Fd4C (100 mg/kg; i.p.; daily, for 7 d) has antihepadnavirus potency in HBV-transgenic mice[1]. Animal Model: |
| Name | L-2'-Fd4C |
| CAS | 221662-50-6 |
| Formula | C9H10FN3O3 |
| Molar Mass | 227.19 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Chen H, et, al. Antiviral activity and pharmacokinetics of 1-(2,3-dideoxy-2-fluoro-beta-L-glyceropent-2-enofuranosyl)cytosine. Antimicrob Agents Chemother. 2003 Jun;47(6):1922-8. |