| Bioactivity | Kobusine derivative-2, a kobusine derivative, has antiproliferative activity against cancer cells. Kobusine derivative-2 can induce the arrest of MDA-MB-231 cells in the sub-G1 phase. Anticancer activity[1]. |
| Invitro | Kobusine derivative-2 (compound 25) (0-20 μM; 72 h) has antiproliferative activity against cancer cell lines A549, MDA-MB-231, MCF-7, KB and KB-VIN[1].Kobusine derivative-2 (12 or 24 h; 13.3 μM) arrests MDA-MB-231 cells at the sub-G1 phase[1]. Cell Proliferation Assay[1] Cell Line: |
| Name | Kobusine derivative-2 |
| Formula | C36H35Cl4NO4 |
| Molar Mass | 687.48 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Koji Wada, et al. Discovery of C20-Diterpenoid Alkaloid Kobusine Derivatives Exhibiting Sub-G1 Inducing Activity. American Chemical Society. 2022 |
Kobusine derivative-2
CAS: F: C36H35Cl4NO4 W: 687.48
Kobusine derivative-2, a kobusine derivative, has antiproliferative activity against cancer cells. Kobusine derivative-2
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