Bioactivity | Kobusine derivative-1 is a Kobusine derivative. Kobusine derivative-1 shows antiproliferative activities against cancer cells[1]. |
Invitro | Kobusine derivative-1 (0-20 μM; 72 h) exhibits significant antiproliferative activities against five human cancer cell lines[1].Kobusine derivative-1 (13.5 μM; 12 or 24 h) treatment likely induces apoptosis within 12 h, decreases numbers of cells in S and G2/M phases, resulting in accumulation of sub-G1[1]. Cell Proliferation Assay[1] Cell Line: |
Name | Kobusine derivative-1 |
Formula | C36H33F6NO4 |
Molar Mass | 657.64 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Koji Wada, et al. Discovery of C20-Diterpenoid Alkaloid Kobusine Derivatives Exhibiting Sub-G1 Inducing Activity. ACS Omega |