| Bioactivity | Kisspeptin 234, is a 10 amino acid peptide as well as a kisspeptin receptor (KISS1, GPR54) antagonist. Kisspeptin 234 is an analog of Kisspeptin 10[1]. |
| In Vivo | Kisspeptin 234 (1 mg/kg, ip, daily, 28 days) TFA 在博来霉素 (BLM) 诱导的 C57BL/6 小鼠肺纤维化模型中,能够抑制 Kisspeptin-13 的抗纤维化作用,特别是在体重减轻、存活率降低、肺系数增加、大量浸润方面[1]。 |
| Name | Kisspeptin 234 |
| CAS | 1145998-81-7 |
| Sequence | Ac-Ala-Asn-Trp-Asn-Gly-Phe-Gly-Trp-Arg-Phe-NH2 |
| Shortening | Ac-ANWNGFGWRF-NH2 |
| Formula | C63H78N18O13 |
| Molar Mass | 1295.41 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Lei Z, et al. Kisspeptin‑13 inhibits bleomycin‑induced pulmonary fibrosis through GPR54 in mice. Mol Med Rep. 2019 Aug;20(2):1049-1056. |