| Bioactivity | Kiss2 peptide acetate is the acetate form of Kiss2 pepride (HY-P10256). Kiss2 peptide acetate is a positive regulator of reproduction. Kiss2 peptide acetate binds with its cognate receptor Kiss2R (GPR54) in COS-7 cells, activates PKA and PKC signaling pathways through Gas and Gaq proteins, and thus enhances the activity of cAMP response element-dependent luciferase (CRE-luc) and serum response element-dependent luciferase (SRE-luc)[1]. |
| Sequence | Phe-Asn-Phe-Asn-Pro-Phe-Gly-Leu-Arg-Phe-NH2 |
| Shortening | FNFNPFGLRF-NH2 |
| Formula | C63H84N16O12.xC2H4O2 |
| Molar Mass | 1257.44 (free base) |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Wang B, et al., Inhibitory action of tongue sole LPXRFa, the piscine ortholog of gonadotropin-inhibitory hormone, on the signaling pathway induced by tongue sole kisspeptin in COS-7 cells transfected with their cognate receptors. Peptides. 2017 Sep;95:62-67. |
Kiss2 peptide acetate
CAS: F: C63H84N16O12.xC2H4O2 W: 1257.44 (free base)
Kiss2 peptide acetate is the acetate form of Kiss2 pepride (HY-P10256). Kiss2 peptide acetate is a positive regulator of
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