| Bioactivity | Kinetin triphosphate(6-Fu-ATP; KTP) is an ATP analogue that regulates or enhances kinase function with higher catalytic efficiency than its endogenous substrate, ATP. Kinetin triphosphate can be used in Parkinson's disease research[1]. |
| Invitro | Kinetin triphosphate 可以作为 PINK1 的磷酸供体来识别 T257 自磷酸化位点,可以在体外 HeLa 细胞中将 PINK1 G309D 催化活性恢复到接近 WT水平[1]。 |
| Name | Kinetin triphosphate |
| CAS | 1450894-16-2 |
| Formula | C15H20N5O14P3 |
| Molar Mass | 587.27 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Nicholas T Hertz, et al. A neo-substrate that amplifies catalytic activity of parkinson's-disease-related kinase PINK1. Cell. 2013 Aug 15;154(4):737-47. |