Bioactivity | Kinetin triphosphate(6-Fu-ATP) tetrasodium is an ATP analogue that regulates or enhances kinase function with higher catalytic efficiency than its endogenous substrate, ATP. Kinetin triphosphate tetrasodium can be used in Parkinson's disease research[1]. |
Invitro | Kinetin triphosphate tetrasodium 可以作为 PINK1 的磷酸供体来识别 T257 自磷酸化位点,可以在体外 HeLa 细胞中将 PINK1 G309D 催化活性恢复到接近 WT水平[1]。Immune: MEFs [1] 0 --> Kinetin triphosphate tetrasodium 相关抗体: |
Name | Kinetin triphosphate tetrasodium |
Formula | C15H16N5Na4O14P3 |
Molar Mass | 675.19 |
Appearance | Solid |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | 4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
Reference | [1]. Nicholas T Hertz, et al. A neo-substrate that amplifies catalytic activity of parkinson's-disease-related kinase PINK1. Cell. 2013 Aug 15;154(4):737-47. |