| Bioactivity | Kifunensine, a potent and selective inhibitor of class I α-mannosidases isolated from Actinomycete, prevents α-mannosidases I from trimming mannose residues on glycoproteins. Kifunensine inhibits ERAD[1][2][3]. | |||||||||
| Invitro | Kifunensine, an alkaloid from actinomycete Kitasatosporia kifunense 9482, is the most efficient nhibitor of a-mannosidase I, blocking N-glycan synthesis at an8GlcNAc2 (Man8) or Man9GlcNAc2 (Man9) stage[3]. RT-PCR[3]. Cell Line: | |||||||||
| Name | Kifunensine | |||||||||
| CAS | 109944-15-2 | |||||||||
| Formula | C8H12N2O6 | |||||||||
| Molar Mass | 232.19 | |||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | |||||||||
| Storage |
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