| Bioactivity | Ki11502 is an effective and selective inhibitor of the PDGF β receptor. Ki11502 selectively inhibits the phosphorylation, proliferation, and proteoglycan synthesis of the PDGF β receptor in human vascular smooth muscle cells. Ki11502 is highly suitable for studying the role of PDGF in vascular diseases, particularly the role of proteoglycans in atherosclerosis[1]. |
| CAS | 347155-76-4 |
| Formula | C26H23N3O4S |
| Molar Mass | 473.54 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Getachew R, et al. Characterisation of Ki11502 as a potent inhibitor of PDGF beta receptor-mediated proteoglycan synthesis in vascular smooth muscle cells. Eur J Pharmacol. 2010;626(2-3):186-192. |