PeptideDB

Kalata B7

CAS: 339532-29-5 F: C128H196N36O40S6 W: 3071.53

Kalata B7 is a cyclotide that can be isolated from Oldenlandia affinis DC (Rubiaceae) and possesses membrane-permeating
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Bioactivity Kalata B7 is a cyclotide that can be isolated from Oldenlandia affinis DC (Rubiaceae) and possesses membrane-permeating capabilities. Kalata B7 is also a partial agonist of oxytocin- and vasopressin V1a- receptors[1][2].
CAS 339532-29-5
Sequence Arg-Asn-Gly-Leu-Pro-Val-Cys-Gly-Glu-Thr-Cys-Thr-Leu-Gly-Thr-Cys-Tyr-Thr-Gln-Gly-Cys-Thr-Cys-Ser-Trp-Pro-Ile-Cys-Lys (Disulfidebridge:Cys7-Cys21;Cys11-Cys23;Cys16-Cys28)
Shortening RNGLPVCGETCTLGTCYTQGCTCSWPICK (Disulfidebridge:Cys7-Cys21;Cys11-Cys23;Cys16-Cys28)
Formula C128H196N36O40S6
Molar Mass 3071.53
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Strömstedt AA, et al. Selective membrane disruption by the cyclotide kalata B7: complex ions and essential functional groups in the phosphatidylethanolamine binding pocket. Biochim Biophys Acta. 2016;1858(6):1317-1327. [2]. Taghizadeh MS, et al. Discovery of the cyclotide caripe 11 as a ligand of the cholecystokinin-2 receptor. Sci Rep. 2022 Jun 2;12(1):9215.