PeptideDB

Kainic acid hydrate

CAS: 58002-62-3 F: C10H17NO5 W: 231.25

Kainic acid hydrate is a potent excitotoxic agent. Kainic acid hydrate also is an agonist for a subtype of ionotropic gl
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Bioactivity Kainic acid hydrate is a potent excitotoxic agent. Kainic acid hydrate also is an agonist for a subtype of ionotropic glutamate receptor. Kainic acid hydrate induces seizures[1][2].
In Vivo Kainic acid hydrate (5 mg/kg;腹腔注射;每小时一次至少 3 小时,直至癫痫持续状态) 诱导大鼠癫痫发作[1]。 Animal Model:
Name Kainic acid hydrate
CAS 58002-62-3
Formula C10H17NO5
Molar Mass 231.25
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Cincioğlu-Palabiyik M, et al. Chronic levetiracetam decreases hippocampal and testicular aromatase expression in normal but not kainic acid-induced experimental model of acute seizures in rats. Neuroreport. 2017 Sep 27;28(14):903-909. [2]. Wang Q, et al. Kainic acid-mediated excitotoxicity as a model for neurodegeneration. Mol Neurobiol. 2005;31(1-3):3-16.