| Bioactivity | KTX-582 intermediate-3 is an intermediate in the synthesis of KTX-582 (HY-148274) and can be used for ADC preparation. KTX-582 is an IRAK4 degrader and inducer of apoptosis with DC50 of 4 nM and 5 nM for IRAK4 and Ikaros, respectively[1]. |
| Name | KTX-582 intermediate-3 |
| CAS | 2573304-30-8 |
| Formula | C26H29F3N4O4 |
| Molar Mass | 518.53 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Mainolfi, et al. Preparation of heterocycles as IRAK degraders and uses thereof. World Intellectual Property Organization, WO2020264499 A1. 2020-12-03. |
KTX-582 intermediate-3
CAS: 2573304-30-8 F: C26H29F3N4O4 W: 518.53
KTX-582 intermediate-3 is an intermediate in the synthesis of KTX-582 (HY-148274) and can be used for ADC preparation. K
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