| Bioactivity | KTX-582 intermediate-1 is an intermediate in the synthesis of KTX-582 (HY-148274) and can be used for ADC preparation. KTX-582 is an IRAK4 degrader and inducer of apoptosis with DC50 of 4 nM and 5 nM for IRAK4 and Ikaros, respectively[1]. | ||||||||||||
| Name | KTX-582 intermediate-1 | ||||||||||||
| CAS | 845508-29-4 | ||||||||||||
| Formula | C16H22O5S | ||||||||||||
| Molar Mass | 326.41 | ||||||||||||
| Appearance | 固体 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Mainolfi, et al. Preparation of heterocycles as IRAK degraders and uses thereof. World Intellectual Property Organization, WO2022147465 A1. 2022-07-07. |
KTX-582 intermediate-1
CAS: 845508-29-4 F: C16H22O5S W: 326.41
KTX-582 intermediate-1 is an intermediate in the synthesis of KTX-582 (HY-148274) and can be used for ADC preparation. K
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