| Bioactivity | KT172 is a DAGLβ inhibitor with an IC50 value of 11 nM. KT172 can be used for the research of metabolic and inflammatory[1]. |
| Target | IC50: 11 nM (DAGLβ) |
| Invitro | KT172 (0-100 μM) has DAGLβ inhibition activity with an IC50 value of 11 nM[1]. KT172 (2 µM) blocks probe-labeling of DAGLβ and ABHD6 activities[1]. KT172 (100 nM, 4 h) blocks DAGLβ activity in situ in the human prostate cancer cell line PC3 with high selectivity[1]. Western Blot Analysis[1] Cell Line: |
| Name | KT172 |
| CAS | 1402612-56-9 |
| Formula | C28H28N4O2 |
| Molar Mass | 452.55 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Ku-Lung Hsu, et al. DAGLβ inhibition perturbs a lipid network involved in macrophage inflammatory responses. Nat Chem Biol. 2012 Dec;8(12):999-1007. |