| Bioactivity | KRFK, a peptide derived from TSP-1, can activate TGF-β. KRFK promotes TGF-β-mediated signaling and its downstream role, independent of thrombospondin (TSP) receptors such as CD47 and CD36. KRFK can be used for chronic ocular surface inflammatory disorders reseach[1]. |
| Invitro | KRFK (50 μm; 24 h) 激活 TGF-β 的分泌，降低 TSP-1 缺陷骨髓源性树突状细胞 (BMDCs) 中 DC 成熟标记物的表达[1]。 |
| Name | KRFK |
| CAS | 162290-78-0 |
| Sequence | Lys-Arg-Phe-Lys |
| Shortening | KRFK |
| Formula | C27H47N9O5 |
| Molar Mass | 577.72 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |