Bioactivity | KRASG12D-IN-3 is an orally active KRASG12D inhibitor that inhibits the cell growth of AGS and AsPC-1 cells with IC50 values of 0.38 nM and 1.23 nM, respectively (WO2024061370A1, compound Z1084)[1]. |
Formula | C31H30ClF6N7O2 |
Molar Mass | 682.06 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Tao Jiang, et al. Pyrimidine-fused ring compound, and preparation method therefor and use thereof. WO2024061370A1. |